About the Authors

Yibing Wu

Contributed equally to this work with: Yibing Wu, Marco Punta

Current address: Pharmaceutical Chemistry Department, University of California San Francisco, San Francisco, California, United States of America

Affiliations Department of Chemistry, State University of New York at Buffalo, Buffalo, New York, United States of America, Northeast Structural Genomics Consortium

Marco Punta

Contributed equally to this work with: Yibing Wu, Marco Punta

Current address: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Affiliations Department of Computer Science and Institute for Advanced Study, Technical University of Munich, Munich, Germany, Northeast Structural Genomics Consortium

Rong Xiao

Affiliations Center of Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, New Jersey, United States of America, Northeast Structural Genomics Consortium

Thomas B. Acton

Affiliations Center of Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, New Jersey, United States of America, Northeast Structural Genomics Consortium

Bharathwaj Sathyamoorthy

Affiliation Department of Chemistry, State University of New York at Buffalo, Buffalo, New York, United States of America

Fabian Dey

Current address: Division of Molecular Biosciences, Imperial College London, London, United Kingdom

Affiliations Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America, Northeast Structural Genomics Consortium

Markus Fischer

Current address: Schrödinger, New York, New York, United States of America

Affiliations Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America, Northeast Structural Genomics Consortium

Arne Skerra

Affiliation Munich Center for Integrated Protein Science, CIPS-M, and Lehrstuhl für Biologische Chemie, Technische Universität München, Freising-Weihenstephan, Germany

Burkhard Rost

Affiliations Department of Computer Science and Institute for Advanced Study, Technical University of Munich, Munich, Germany, Northeast Structural Genomics Consortium

Gaetano T. Montelione

Affiliations Center of Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, New Jersey, United States of America, Northeast Structural Genomics Consortium

Thomas Szyperski

szypersk@buffalo.edu

Affiliations Department of Chemistry, State University of New York at Buffalo, Buffalo, New York, United States of America, Northeast Structural Genomics Consortium

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YW RX TBA BS GTM TS. Performed the experiments: YW RX TBA BS. Analyzed the data: YW MP RX TBA BS FD MF AS BR GTM TS. Contributed reagents/materials/analysis tools: MP RX TBA FD MF BR GTM TS. Wrote the paper: YW MP AS BR GTM TS.