About the Authors
- Gregory C. Ippolito
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Affiliation Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, Texas, United States of America
- Kam Hon Hoi
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Affiliation Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas, United States of America
- Sai T. Reddy
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Affiliation Department of Biosystems Science and Engineering, Eidgenössische Technische Hochschule Zurich, Zurich, Switzerland
- Sean M. Carroll
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Affiliation Department of Chemical Engineering, University of Texas at Austin, Austin, Texas, United States of America
- Xin Ge
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Affiliation Chemical and Environmental Engineering, University of California, Riverside, California, United States of America
- Tobias Rogosch
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Affiliation Department of Pediatrics, Philips-University, Marburg, Germany
- Michael Zemlin
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Affiliation Department of Pediatrics, Philips-University, Marburg, Germany
- Leonard D. Shultz
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Affiliation The Jackson Laboratory, Bar Harbor, Maine, United States of America
- Andrew D. Ellington
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Affiliation Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America
- Carla L. VanDenBerg
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Affiliation Department of Pharmacology and Toxicology, University of Texas at Austin, Austin, Texas, United States of America
- George Georgiou
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* E-mail: gg@che.utexas.edu
Affiliations Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, Texas, United States of America, Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas, United States of America, Department of Chemical Engineering, University of Texas at Austin, Austin, Texas, United States of America, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: GCI KHH STR SMC. Performed the experiments: GCI KHH STR CLV. Analyzed the data: ADE GCI KHH STR GG. Wrote the paper: GCI KHH STR GG. Wrote data-mining scripts for repertoire analysis: KHH XG. Developed flow cytometry methods: SMC STR. Wrote and executed data-mining scripts for CDR-H3 and SHM analysis: TR MZ. Provided NOD-scid-IL2Rgnull mice and contributed to editing of the manuscript: LDS. Provided critical advice: ADE. Initiated the project: STR GG.