JC Virus T-Antigen Regulates Glucose Metabolic Pathways in Brain Tumor Cells

Evan Noch; Ilker Kudret Sariyer; Jennifer Gordon; Kamel Khalili

doi:10.1371/journal.pone.0035054

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Peer-reviewed

Research Article

JC Virus T-Antigen Regulates Glucose Metabolic Pathways in Brain Tumor Cells

Evan Noch,

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Ilker Kudret Sariyer,

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Jennifer Gordon,

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Kamel Khalili

* E-mail: kamel.khalili@temple.edu

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

JC Virus T-Antigen Regulates Glucose Metabolic Pathways in Brain Tumor Cells

Evan Noch,
Ilker Kudret Sariyer,
Jennifer Gordon,
Kamel Khalili

Published: April 9, 2012
https://doi.org/10.1371/journal.pone.0035054

About the Authors

Evan Noch

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Ilker Kudret Sariyer

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Jennifer Gordon

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Kamel Khalili

* E-mail: kamel.khalili@temple.edu

Affiliation Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KK EN JG. Performed the experiments: EN JG IS. Analyzed the data: KK JG EN. Contributed reagents/materials/analysis tools: KK JG. Wrote the paper: KK JG EN.

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Glucose
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Glucose metabolism
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Cell cycle and cell division
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Malignant tumors
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Cancers and neoplasms
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Cyclins
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Reactive oxygen species
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Phosphates
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