About the Authors
- Gregory J. Metzger
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Affiliation Department of Radiology, University of Minnesota, Minneapolis, Minnesota, United States of America
- Stephen C. Dankbar
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Affiliation Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, United States of America
- Jonathan Henriksen
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Affiliations Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, United States of America, BioNet, University of Minnesota, Minneapolis, Minnesota, United States of America
- Anthony E. Rizzardi
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Affiliation Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, United States of America
- Nikolaus K. Rosener
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Affiliation Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, United States of America
- Stephen C. Schmechel
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* E-mail: schme004@umn.edu
Affiliations Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, United States of America, BioNet, University of Minnesota, Minneapolis, Minnesota, United States of America
Competing Interests
Dr. Metzger, Dr. Dankbar, Dr. Henricksen and Dr. Schmechel, are co-developers of the methods to generate signature maps from digitized immunohistochemistry slides described in this manuscript. These methods have been licensed from the University of Minnesota to Flagship Biosciences, LLC. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: GJM SCS. Performed the experiments: SCD JH AER NKR SCS. Analyzed the data: GJM JH AER NKR. Contributed reagents/materials/analysis tools: GJM SCS. Wrote the paper: GJM SCD JH AER NKR SCS. Programmed the Java Software interface: SCD.