About the Authors

Sirada Srihirun

Affiliation Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand

Thanaporn Sriwantana

Affiliation Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand

Supeenun Unchern

Affiliation Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand

Dusadee Kittikool

Affiliation Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand

Egarit Noulsri

Affiliation Office for Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Kovit Pattanapanyasat

Affiliation Office for Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Suthat Fucharoen

Affiliation Thalassemia Research Center, Institute of Science and Technology for Research and Development, Mahidol University, Nakhonpathom, Thailand

Barbora Piknova

Affiliation Molecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Alan N. Schechter

Affiliation Molecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Nathawut Sibmooh

scnsm@mahidol.ac.th

Affiliation Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand

Competing Interests

A.N. Schechter and N. Sibmooh are co-inventors of a patent issued to NIH for the use of nitrite in the treatment of cardiovascular diseases. None of the authors has any conflict of interest. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SS SF BP ANS NS. Performed the experiments: SS TS SU EN KP DK. Analyzed the data: SS BP ANS NS. Contributed reagents/materials/analysis tools: SF SU ANS NS. Wrote the paper: SS NS ANS BP.