About the Authors

Jennifer M. Reynolds

Affiliation DNA and BioFluids Research Center of Emphasis, Pfizer Global Research and Development, Groton, Connecticut, United States of America

Sara A. Paciga

Affiliation Precision Medicine, Pfizer Global Research and Development, Groton, Connecticut, United States of America

Frances A. Sanders

Affiliation Precision Medicine, Pfizer Global Research and Development, Sandwich, Kent, United Kingdom

Craig L. Hyde

Affiliation Biostatistics, Pfizer Global Research and Development, Groton, Connecticut, United States of America

A. Katrina Loomis

Affiliation Precision Medicine, Pfizer Global Research and Development, Groton, Connecticut, United States of America

Geoffrey I. Johnston

Geoff.Johnston@astrazeneca.com

Current address: AstraZeneca Research and Development, Mölndal, Sweden

Affiliation Precision Medicine, Pfizer Global Research and Development, Sandwich, Kent, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following conflicts: All authors are employed by Pfizer Inc. and hold stock in Pfizer Inc. However, this does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GIJ JMR SAP FAS AKL. Performed the experiments: JMR GIJ AKL. Analyzed the data: JMR GIJ FAS CLH. Contributed reagents/materials/analysis tools: JMR GIJ AKL SAP CLH. Wrote the paper: GIJ JMR SAP FAS AKL CLH.