About the Authors

Prabhakar Rajan

Contributed equally to this work with: Prabhakar Rajan, Caroline Dalgliesh

Affiliations Institute of Human Genetics, Newcastle University, Newcastle-upon-Tyne, United Kingdom, Beatson Institute for Cancer Research, Glasgow, United Kingdom, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom

Caroline Dalgliesh

Contributed equally to this work with: Prabhakar Rajan, Caroline Dalgliesh

Affiliation Institute of Human Genetics, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Phillippa J. Carling

Affiliation Institute of Human Genetics, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Thomas Buist

Affiliation Institute of Human Genetics, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Chaolin Zhang

Current address: Howard Hughes Medical Institute, Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, United States of America

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Sushma N. Grellscheid

Affiliation Institute of Human Genetics, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Kelly Armstrong

Affiliation Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Jacqueline Stockley

Affiliation Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Cedric Simillion

Affiliation Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Luke Gaughan

Affiliation Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Gabriela Kalna

Affiliation Beatson Institute for Cancer Research, Glasgow, United Kingdom

Michael Q. Zhang

Current address: Center for Systems Biology, The University of Texas at Dallas, Richardson, Texas, United States of America

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Craig N. Robson

Affiliation Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Hing Y. Leung

Affiliations Beatson Institute for Cancer Research, Glasgow, United Kingdom, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom

David J. Elliott

david.elliott@ncl.ac.uk

Affiliation Institute of Human Genetics, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PR JS LG HYL DJE. Performed the experiments: PR CD KA JS LG. Analyzed the data: PR PC TB CZ SNG CS GK. Contributed reagents/materials/analysis tools: MQZ CNR HYL DJE. Wrote the paper: PR HYL DJE.