About the Authors

Brian A. Ference, Wonsuk Yoo, John M. Flack
Division of Translational Research and Clinical Epidemiology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan, United States of America

Brian A. Ference, Michael Clarke
Centre for Evidence Based Medicine, University of Oxford, Oxford, United Kingdom

Wonsuk Yoo
Division of Biostatistics and Epidemiology, University of Tennessee Health Sciences Center, Memphis, Tennessee, United States of America

Michael Clarke
Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom

Michael Clarke
All-Ireland Hub for Trials Methodology Research, Queen's University Belfast, Belfast, United Kingdom

Corresponding Author


Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BAF WY JMF MC. Performed the experiments: BAF WY. Analyzed the data: BAF WY JMF MC. Wrote the paper: BAF WY JMF MC.