About the Authors
- Rafael C. Dutra
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Contributed equally to this work with: Rafael C. Dutra, Rafaela F. Claudino
Affiliation Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil
- Rafaela F. Claudino
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Contributed equally to this work with: Rafael C. Dutra, Rafaela F. Claudino
Affiliation Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil
- Allisson F. Bento
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Affiliation Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil
- Rodrigo Marcon
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Affiliation Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil
- Éder C. Schmidt
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Affiliation Department of Cell Biology, Embryology and Genetics, Central Laboratory of Electron Microscopy, Universidade Federal de Santa Catarina, Florianópolis, Brazil
- Zenilda L. Bouzon
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Affiliation Department of Cell Biology, Embryology and Genetics, Central Laboratory of Electron Microscopy, Universidade Federal de Santa Catarina, Florianópolis, Brazil
- Luiz F. Pianowski
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Affiliation Pianowski and Pianowski Ltda., São Paulo, Brazil
- João B. Calixto
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* E-mail: calixto@farmaco.ufsc.br
Affiliation Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil
Competing Interests
Luiz Francisco Pianowski is proprietor of the contract research organization Pianowski & Pianowski Ltda. He has received consulting fees from Amazônia Fitomedicamentos. In addition, Luiz F. Pianowski performed previous chemical characterization of euphol and provided it for this study. Luiz Francisco Pianowski and João Batista Calixto are assigned in the patent on the analgesic action of euphol as inventors. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: RCD RFC AFB RM JBC. Performed the experiments: RCD RFC AFB RM ECS ZLB. Analyzed the data: RCD RFC AFB. Contributed reagents/materials/analysis tools: LFP JBC. Wrote the paper: RCD RFC JBC.