About the Authors

Cheng-Hsien Wu

Affiliations Department of Chemistry, University of Wisconsin, Madison, Wisconsin, United States of America, Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

Siyuan Chen

Affiliation Department of Chemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Michael R. Shortreed

Affiliation Department of Chemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Gloria M. Kreitinger

Affiliation Department of Chemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Yuan Yuan

Affiliation Department of Chemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Brian L. Frey

Affiliation Department of Chemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Yi Zhang

Affiliation Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

Shama Mirza

Affiliations Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

Lisa A. Cirillo

Affiliation Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

Michael Olivier

Affiliations Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

Lloyd M. Smith

smith@chem.wisc.edu

Affiliations Department of Chemistry, University of Wisconsin, Madison, Wisconsin, United States of America, Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Genome Center of Wisconsin, Madison, Wisconsin, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: C-HW SC MRS MO LMS. Performed the experiments: C-HW SC GMK YY. Analyzed the data: C-HW SC GMK. Contributed reagents/materials/analysis tools: LAC YZ SM. Wrote the paper: C-HW SC MRS LMS. Revised the manuscript: BLF.