About the Authors

Fumihiko Hakuno

Affiliation Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Yoko Yamauchi

Current address: Hair Clinic Reve-21 Corporation, Chuo-ku, Osaka, Japan

Affiliation Department of Bioengineering Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Aichi, Japan

Gen Kaneko

Current address: Laboratory of Marine Biochemistry, Department of Aquatic Bioscience, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Affiliation Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Yosuke Yoneyama

Affiliation Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Jun Nakae

Affiliation Frontier Medicine on Metabolic Syndrome, Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Kazuhiro Chida

Affiliation Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Tatsuhiko Kadowaki

Affiliation Department of Bioengineering Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Aichi, Japan

Keitaro Yamanouchi

Affiliation Department of Veterinary Medical Science, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Masugi Nishihara

Affiliation Department of Veterinary Medical Science, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Shin-Ichiro Takahashi

atkshin@mail.ecc.u-tokyo.ac.jp

Affiliation Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FH Y. Yamauchi GK KC TK KY MN S-IT. Performed the experiments: FH Y. Yamauchi GK Y. Yoneyama JN S-IT. Analyzed the data: FH Y. Yamauchi GK Y. Yoneyama JN S-IT. Contributed reagents/materials/analysis tools: FH JN KY S-IT. Wrote the paper: FH Y. Yamauchi GK KY MN S-IT. Primary responsibility for final content: S-IT. Read and approved the final manuscript: FH Y. Yamauchi GK Y. Yoneyama JN KC TK KY MN S-IT.