About the Authors
- Qingping Xu
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, United States of America
- Neil D. Rawlings
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Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, United Kingdom
- Hsiu-Ju Chiu
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, United States of America
- Lukasz Jaroszewski
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Center for Research in Biological Systems, University of California San Diego, La Jolla, California, United States of America, Program on Bioinformatics and Systems Biology, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America
- Heath E. Klock
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Protein Sciences Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Mark W. Knuth
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Protein Sciences Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Mitchell D. Miller
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, United States of America
- Marc-Andre Elsliger
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America
- Ashley M. Deacon
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, United States of America
- Adam Godzik
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Center for Research in Biological Systems, University of California San Diego, La Jolla, California, United States of America, Program on Bioinformatics and Systems Biology, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America
- Scott A. Lesley
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Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Protein Sciences Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America, Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America
- Ian A. Wilson
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* E-mail: wilson@scripps.edu
Affiliations Joint Center for Structural Genomics, La Jolla, California, United States of America, Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America
Competing Interests
Heath E. Klock, Mark W. Knuth and Scott A. Lesley are employees of the Novartis Research Foundation. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: QX MAE AMD AG SAL IAW. Performed the experiments: QX. Analyzed the data: QX NDR. Contributed reagents/materials/analysis tools: HJC LJ HEK MWK MDM. Wrote the paper: QX NDR AMD MAE IAW.