About the Authors
- Unnur S. Bjornsdottir
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Contributed equally to this work with: Unnur S. Bjornsdottir, Stephen T. Holgate
Affiliation Department of Allergy/Clinical Immunology, University of Iceland, Reykjavík, Iceland
- Stephen T. Holgate
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Contributed equally to this work with: Unnur S. Bjornsdottir, Stephen T. Holgate
* E-mail: margot.otoole@pfizer.com (MOT); S.Holgate@soton.ac.uk (STH)
Affiliation University of Southampton, Southampton, United Kingdom
- Padmalatha S. Reddy
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Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- Andrew A. Hill
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Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- Charlotte M. McKee
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Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America
- Cristina I. Csimma
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Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America
- Amy A. Weaver
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Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- Holly M. Legault
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Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America
- Clayton G. Small
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Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America
- Renee C. Ramsey
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Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- Debra K. Ellis
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Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America
- Conor M. Burke
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Affiliation James Connolly Memorial Hospital, Dublin, Ireland
- Philip J. Thompson
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Affiliation Lung Institute of WA and Centre for Asthma, Allergy & Respiratory Research, University of Western Australia, Crawley, Australia
- Peter H. Howarth
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Affiliation University of Southampton, Southampton, United Kingdom
- Andrew J. Wardlaw
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Affiliation University of Leicester, Leicester, United Kingdom
- Phillip G. Bardin
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Affiliation Monash University and Medical Centre, Melbourne, Australia
- David I. Bernstein
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Affiliation University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
- Louis B. Irving
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Affiliation Royal Melbourne Hospital, Parkville, Australia
- Geoffrey L. Chupp
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Affiliation Yale University School of Medicine, New Haven, Connecticut, United States of America
- George W. Bensch
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Affiliation Bensch Clinical Research, Stockton, California, United States of America
- Gregory W. Bensch
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Affiliation Bensch Clinical Research, Stockton, California, United States of America
- Jon E. Stahlman
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Affiliation Allergy and Asthma Center, Conyers, Georgia, United States of America
- Monroe Karetzky
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Affiliation Newark Beth Israel Medical Center, Newark, New Jersey, United States of America
- James W. Baker
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Affiliation Baker Allergy, Asthma and Dermatology, Lake Oswego, Oregon, United States of America
- Rachel L. Miller
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Affiliation Columbia University Medical Center, New York, New York, United States of America
- Brad H. Goodman
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Affiliation Coastal Allergy and Asthma, Savannah, Georgia, United States of America
- Donald G. Raible
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Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- Samuel J. Goldman
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Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- Douglas K. Miller
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Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- John L. Ryan
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Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America
- Andrew J. Dorner
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Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America
- Frederick W. Immermann
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¶These authors also contributed equally to this work.
Affiliation Pfizer, Cambridge, Massachusetts, United States of America
- Margot O'Toole
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* E-mail: margot.otoole@pfizer.com (MOT); S.Holgate@soton.ac.uk (STH)
Affiliation Pfizer, Cambridge, Massachusetts, United States of America
Competing Interests
The funding for this study was provided by Wyeth (now Pfizer) and company employees participated in the design, execution and analysis of the study. The names of the authors were employed by Wyeth (now Pfizer) at the time the study are: Padmalatha S. Reddy, Andrew A. Hill, Charlotte M. McKee, Cristina I. Csimma, Amy A. Weaver, Holly M. Legault, Clayton G. Small, Renee C. Ramsey, Debra K. Ellis, Donald G. Raible, Samuel J. Goldman, Douglas K. Miller, John L. Ryan, Andrew J. Dorner, Frederick W. Immermann, Margot O'Toole. Many of these authors also held stock and/or stock options. A patent application was also filed based on this study - Published application number 20090325176. Title: Gene Expression Profiles Associated with Asthma Exacerbation Attacks None of the disclosures above alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. The authors point out that no investigative drug was used in this study, and that therefore, bias based on potential financial benefit interests is not an issue. Moreover, proceeds from patents do not accrue to employees. Non-employee authors received fees to cover cost related to running the study.
Author Contributions
Conceived and designed the experiments: JLR CIC AJD SJG. Performed the experiments: AAW HML CGS RCR DKE. Analyzed the data: STH USB PSR AAH DKM FWI MO DGR. Wrote the paper: MO STH PSR AAH FWI USB. Participated in study design, recruited patients, performed study procedures: USB STH CMB PJT AJW PGB DIB LBI GLC GWB GWB JWB. Recruited subjects, performed study procedures: PHH JES RLM MK BHG. Medical Monitor: CMM.