About the Authors
- Jianbiao Zhou
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Affiliation Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
- Chonglei Bi
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Affiliation Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
- Wee-Joo Chng
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* E-mail: mdcccs@nus.edu.sg (C-SC); mdccwj@nus.edu.sg (W-JC)
Affiliations Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Department of Hematology-Oncology, National University Hospital, Singapore, Singapore
- Lip-Lee Cheong
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Affiliation Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
- Shaw-Cheng Liu
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Affiliation Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
- Sylvia Mahara
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Affiliation Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
- Kian-Ghee Tay
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Affiliation Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
- Qi Zeng
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Affiliation Institute of Molecular and Cell Biology (IMCB), A*Star, Biopolis, Singapore, Singapore
- Jie Li
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Affiliation Institute of Molecular and Cell Biology (IMCB), A*Star, Biopolis, Singapore, Singapore
- Ke Guo
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Affiliation Institute of Molecular and Cell Biology (IMCB), A*Star, Biopolis, Singapore, Singapore
- Cheng Peow Bobby Tan
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Affiliation Institute of Molecular and Cell Biology (IMCB), A*Star, Biopolis, Singapore, Singapore
- Hanry Yu
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Affiliations Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Institute of Biotechnology and Nanotechnology, A*Star, Biopolis, Singapore, Singapore
- Daniel H. Albert
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Affiliation Abbott Laboratories, Chicago, Illinois, United States of America
- Chien-Shing Chen
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* E-mail: mdcccs@nus.edu.sg (C-SC); mdccwj@nus.edu.sg (W-JC)
Affiliations Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Division of Hematology and Oncology, School of Medicine, Loma Linda University, Loma Linda, California, United States of America
Competing Interests
One of the authors (D.H.A.) is an employee of Abbott Laboratories, whose potential product was studied in the present work. D.H.A. provided ABT-869 compound but he was not involved in experiment design, data collection and result interpretation. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors. The other authors have declared no conflict of interests.
Author Contributions
Conceived and designed the experiments: JZ W-JC C-SC. Performed the experiments: JZ CB W-JC L-LC S-CL SM K-GT JL KG CPBT. Analyzed the data: JZ W-JC QZ C-SC. Contributed reagents/materials/analysis tools: HY DHA. Wrote the paper: JZ.