About the Authors

Kunimichi Niibe

Affiliations Department of Physiology, Keio University School of Medicine, Tokyo, Japan, Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, Japan

Yoshimi Kawamura

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Daisuke Araki

Affiliations Department of Physiology, Keio University School of Medicine, Tokyo, Japan, Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, Japan

Satoru Morikawa

Affiliation Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, Japan

Kyoko Miura

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Sadafumi Suzuki

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Shigeto Shimmura

Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan

Takehiko Sunabori

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Yo Mabuchi

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Yasuo Nagai

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Taneaki Nakagawa

Affiliation Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, Japan

Hideyuki Okano

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Yumi Matsuzaki

penguin@a8.keio.jp

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualized and designed the experiments: KN HO YM. Performed most of the experiments and analysed the data: KN. Performed blastocyst injection of iPS cells to produce adult chimeras: YK. Assisted with cell sorting and cell culture: DA SM KM. Performed cell sorting and surface marker analysis: S. Suzuki. Assisted with bisulfite genomic sequencing: TS. Commented on the manuscript: S. Shimmura YM YN TN. All authors participated in the discussion.