Moderate Caloric Restriction during Gestation in Rats Alters Adipose Tissue Sympathetic Innervation and Later Adiposity in Offspring

Ana Paula García; Mariona Palou; Juana Sánchez; Teresa Priego; Andreu Palou; Catalina Picó

doi:10.1371/journal.pone.0017313

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Peer-reviewed

Research Article

Moderate Caloric Restriction during Gestation in Rats Alters Adipose Tissue Sympathetic Innervation and Later Adiposity in Offspring

Ana Paula García,

Affiliation Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain
⨯
Mariona Palou,

Affiliation Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain
⨯
Juana Sánchez,

Affiliation Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain
⨯
Teresa Priego,

Affiliation Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain
⨯
Andreu Palou ,

* E-mail: andreu.palou@uib.es

Affiliation Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain
⨯
Catalina Picó

Affiliation Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain
⨯

Moderate Caloric Restriction during Gestation in Rats Alters Adipose Tissue Sympathetic Innervation and Later Adiposity in Offspring

Ana Paula García,
Mariona Palou,
Juana Sánchez,
Teresa Priego,
Andreu Palou,
Catalina Picó

Published: February 18, 2011
https://doi.org/10.1371/journal.pone.0017313

About the Authors

Ana Paula García

Affiliation Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain

Mariona Palou

Juana Sánchez

Teresa Priego

Andreu Palou

* E-mail: andreu.palou@uib.es

Catalina Picó

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AP CP APG. Performed the experiments: APG MP JS TP. Analyzed the data: APG MP. Contributed reagents/materials/analysis tools: APG MP. Wrote the paper: APG CP AP.

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Adipose tissue
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Adipocytes
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Body weight
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Leptin
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Gene expression
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Diet
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Pregnancy
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Immunohistochemical analysis
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