About the Authors

Christian T. Farrar

Contributed equally to this work with: Christian T. Farrar, Walid S. Kamoun, Carsten D. Ley

cfarrar@nmr.mgh.harvard.edu

Affiliation Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Walid S. Kamoun

Contributed equally to this work with: Christian T. Farrar, Walid S. Kamoun, Carsten D. Ley

Affiliation Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Carsten D. Ley

Contributed equally to this work with: Christian T. Farrar, Walid S. Kamoun, Carsten D. Ley

Affiliation Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Young R. Kim

Affiliation Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Ciprian Catana

Affiliation Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Seon J. Kwon

Affiliation Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Bruce R. Rosen

Affiliation Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Rakesh K. Jain

Affiliation Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

A. Gregory Sorensen

Affiliation Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Competing Interests

AGS has advisory roles at Genentech, Regeneron, Millennium Pharmaceuticals, AstraZenca, Mitsubishi Pharma, Merrimack Pharmaceuticals, Olea Medical, Siemens Medical Solutions, Lantheus, Biogen Idec, and Epix Pharmaceuticals. RKJ has advisory roles at AstraZeneca, Dyax, Enlight, SynDevRx, Millennium (1 time), Genzyme (1 time), Morphosys (1 time), Astellas (1 time) and Regeneron (1 time), and received honoraria for giving lectures at Pfizer and Genzyme. The other authors have declared that no competing interests exist. Some financial support was provided by AstraZeneca Pharmaceuticals. The funders do not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CTF WSK CDL BRR RKJ AGS. Performed the experiments: CTF WSK CDL. Analyzed the data: CTF WSK CDL CC SJK YRK. Wrote the paper: CTF WSK YRK BRR AGS.