About the Authors

Kenneth E. S. Poole

kp254@nhs.net

Affiliation Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Graham M. Treece

Affiliation Department of Engineering, University of Cambridge, Cambridge, United Kingdom

Gerard R. Ridgway

Affiliation Institute of Neurology, University College London, London, United Kingdom

Paul M. Mayhew

Affiliation Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Jan Borggrefe

Affiliation Department of Diagnostic Radiology, University of Schleswig Holstein, Kiel, Germany

Andrew H. Gee

Affiliation Department of Engineering, University of Cambridge, Cambridge, United Kingdom

Competing Interests

KESP and GMT are inventors on a related Great Britain patent application GB0917524.1, "Image data processing systems." This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KESP GMT AHG. Performed the experiments: KESP GMT AHG. Analyzed the data: KESP GMT GRR AHG. Contributed reagents/materials/analysis tools: KESP GMT GRR PMM JB AHG. Wrote the paper: KESP GMT GRR PMM JB AHG.