About the Authors

Carol Man Gao

Contributed equally to this work with: Carol Man Gao, Alice Y. Yam

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Alice Y. Yam

Contributed equally to this work with: Carol Man Gao, Alice Y. Yam

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Xuemei Wang

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Erika Magdangal

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Cleo Salisbury

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

David Peretz

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Ronald N. Zuckermann

Address Current address: Lawrence Berkeley National Laboratory, Molecular Foundry, Berkeley, California, United States of America

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Michael D. Connolly

Address Current address: Lawrence Berkeley National Laboratory, Molecular Foundry, Berkeley, California, United States of America

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Oskar Hansson

Affiliation Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden

Lennart Minthon

Affiliation Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden

Henrik Zetterberg

Affiliation Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, Sahlgrenska University Hospital, Mölndal, Sweden

Kaj Blennow

Affiliation Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, Sahlgrenska University Hospital, Mölndal, Sweden

Joseph P. Fedynyshyn

joseph.fedynyshyn@novartis.com

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Sophie Allauzen

Affiliation Research and Development, Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

Competing Interests

Several of the authors are employed by Novartis Vaccines and Diagnostics and thus may have a conflict of interest. In addition, the submitted work is included in a pending patent application on amyloid-beta aggregates as biomarkers for Alzheimer's Disease (patent #61/265,340, submitted by Novartis AG on Nov 30, 2009). This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CMG AYY SA JPF DP. Performed the experiments: CMG EM AYY. Analyzed the data: CMG EM AYY JPF. Contributed reagents/materials/analysis tools: XW CS RNZ MDC OH LM HZ KB. Wrote the paper: AYY.