ADAM2 Interactions with Mouse Eggs and Cell Lines Expressing α4/α9 (ITGA4/ITGA9) Integrins: Implications for Integrin-Based Adhesion and Fertilization

Ulyana V. Desiderio; Xiaoling Zhu; Janice P. Evans

doi:10.1371/journal.pone.0013744

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Open Access

Peer-reviewed

Research Article

ADAM2 Interactions with Mouse Eggs and Cell Lines Expressing α₄/α₉ (ITGA4/ITGA9) Integrins: Implications for Integrin-Based Adhesion and Fertilization

Ulyana V. Desiderio,

Affiliation Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Xiaoling Zhu,

Affiliation Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Janice P. Evans

* E-mail: jpevans@jhsph.edu

Affiliation Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯

ADAM2 Interactions with Mouse Eggs and Cell Lines Expressing α₄/α₉ (ITGA4/ITGA9) Integrins: Implications for Integrin-Based Adhesion and Fertilization

Ulyana V. Desiderio,
Xiaoling Zhu,
Janice P. Evans

Published: October 29, 2010
https://doi.org/10.1371/journal.pone.0013744

About the Authors

Ulyana V. Desiderio

Affiliation Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Xiaoling Zhu

Affiliation Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Janice P. Evans

* E-mail: jpevans@jhsph.edu

Affiliation Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: UVD XZ JPE. Performed the experiments: UVD XZ. Analyzed the data: UVD XZ JPE. Contributed reagents/materials/analysis tools: UVD XZ. Wrote the paper: JPE.

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Integrins
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Immunoprecipitation
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Eggs
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Small interfering RNA
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Cell adhesion
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Ova
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Monoclonal antibodies
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Oocytes
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