About the Authors

Miralem Mrkonjic, Stavroula Raptis, Steven Gallinger, Bharati Bapat
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada

Miralem Mrkonjic, Stavroula Raptis, Vaijayanti V. Pethe, Steven Gallinger, John R. McLaughlin, Bharati Bapat
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Miralem Mrkonjic, Stavroula Raptis, Aaron Pollett, Bharati Bapat
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada

Nicole M. Roslin, Celia M. Greenwood, Theodore Chiang, Andrew D. Paterson
Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada

Celia M. Greenwood, John R. McLaughlin, Andrew D. Paterson
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

Peter W. Laird
University of Southern California Epigenome Center, University of Southern California, Los Angeles, California, United States of America

Darshana Daftary, Steven Gallinger, John R. McLaughlin, Brent W. Zanke
Ontario Familial Colorectal Cancer Registry, Cancer Care Ontario, Toronto, Ontario, Canada

Elizabeth Dicks, Patrick S. Parfrey
Clinical Epidemiology Unit, Memorial University of Newfoundland, St. John's, Newfoundland, Canada

Stephen N. Thibodeau
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

Steven Gallinger
Department of Surgery, University of Toronto, Toronto, Ontario, Canada

H. Banfield Younghusband, Roger C. Green
Discipline of Genetics, Memorial University of Newfoundland, St. John's, Newfoundland, Canada

John D. Potter, Polly A. Newcomb
Public Health Sciences Division, Fred Hutchinson Cancer Research Centre, Seattle, Washington, United States of America

Thomas J. Hudson
Ontario Institute for Cancer Research, Toronto, Ontario, Canada

Thomas J. Hudson
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Thomas J. Hudson
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Brent W. Zanke
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

Corresponding Author

bapat@lunenfeld.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MM NMR CMTG AP BB. Performed the experiments: MM SR AFP PWL VP. Analyzed the data: MM NMR CMTG TC. Contributed reagents/materials/analysis tools: CMTG DD ED ST SG PSP HBY JP TJH JRM RCG BZ PAN AP BB. Wrote the paper: MM NMR JP PAN AP BB.