About the Authors

Sundaravadivel Balasubramanian

balasubr@musc.edu

Affiliation Cardiology Division, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America

Santhosh K. Mani

Affiliation Cardiology Division, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America

Harinath Kasiganesan

Affiliation Cardiology Division, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America

Catalin C. Baicu

Affiliation Cardiology Division, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America

Dhandapani Kuppuswamy

Affiliations Cardiology Division, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America, Ralph H. Johnson Department, Veterans Affairs Medical Center, Charleston, South Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SB. Performed the experiments: SB SKM HK CCB. Analyzed the data: SB. Contributed reagents/materials/analysis tools: DK. Wrote the paper: SB. Produced the Rac N17 adenovirus: SKM. Performed immunohistochemical and some of the immunocytochemical staining: SKM. Isolated cardiomyocytes and performed RVPO surgery: HK. Performed adult feline cardiomyocyte contractility experiments: CCB. Held discussions on the overall design of the experiments and helped in the organization of the manuscript: DK.