About the Authors

Anna Nilsson

Affiliation Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden

Thomas E. Fehniger

Affiliations AstraZeneca R&D, Lund, Sweden, Institute of Clinical Medicine, Tallinn University of Technology, Tallinn, Estonia

Lena Gustavsson

Affiliation AstraZeneca R&D, Lund, Sweden

Malin Andersson

Affiliation Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden

Kerstin Kenne

Affiliation AstraZeneca R&D, Södertälje, Sweden

György Marko-Varga

Affiliations AstraZeneca R&D, Lund, Sweden, Clinical Protein Science and Imagining, Department of Measurement Technology and Industrial Electrical Engineering, Lund University, Lund, Sweden

Per E. Andrén

per.andren@bmms.uu.se

Affiliation Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden

Competing Interests

TF, GM-V, LG, and KK were full-time salaried employees of AstraZeneca R&D and performed this study as part of their regular duties. None of the authors will receive any form of royalty or further financial compensation from AstraZeneca or any private or commercial body for publishing these results. Uppsala University (PE and AN) received financial support from AstraZeneca in the form of payment of contract research in the performance of this study. Neither AstraZeneca nor Uppsala University have commercial products in development or marketed products used within the present study nor commercial interest relating to patents applied for or granted using the specific technology described herein. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AN TEF LG GMV PEA. Performed the experiments: AN TEF MA. Analyzed the data: AN TEF GMV PEA. Contributed reagents/materials/analysis tools: TEF LG KK GMV PEA. Wrote the paper: AN TEF LG GMV PEA.