About the Authors

Dan E. Arking

Contributed equally to this work with: Dan E. Arking, Kyndaron Reinier, Aravinda Chakravarti, Sumeet S. Chugh

Affiliation Center for Complex Diseases Genomics, McKusick-Nathans Institute of Genetic Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Kyndaron Reinier

Contributed equally to this work with: Dan E. Arking, Kyndaron Reinier, Aravinda Chakravarti, Sumeet S. Chugh

Affiliation Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

Wendy Post

Affiliation Division of Cardiology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Jonathan Jui

Affiliation Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon, United States of America

Gina Hilton

Affiliation Center for Complex Diseases Genomics, McKusick-Nathans Institute of Genetic Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Ashley O'Connor

Affiliation Center for Complex Diseases Genomics, McKusick-Nathans Institute of Genetic Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Ronald J. Prineas

Affiliation Department of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina, United States of America

Eric Boerwinkle

Affiliation School of Public Health, University of Texas Health Science Center, Houston, Texas, United States of America

Bruce M. Psaty

Affiliations Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Group Health Research Institute, Group Health, Seattle, Washington, United States of America

Gordon F. Tomaselli

Affiliation Division of Cardiology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Thomas Rea

Affiliation Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, United States of America

Nona Sotoodehnia

Affiliation Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, United States of America

David S. Siscovick

Affiliation Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, United States of America

Gregory L. Burke

Affiliation Department of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina, United States of America

Eduardo Marban

Affiliation Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

Peter M. Spooner

Affiliation Division of Cardiology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Aravinda Chakravarti

Contributed equally to this work with: Dan E. Arking, Kyndaron Reinier, Aravinda Chakravarti, Sumeet S. Chugh

aravinda@jhmi.edu (AC); sumeet.chugh@cshs.org (SSC)

Affiliation Center for Complex Diseases Genomics, McKusick-Nathans Institute of Genetic Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Sumeet S. Chugh

Contributed equally to this work with: Dan E. Arking, Kyndaron Reinier, Aravinda Chakravarti, Sumeet S. Chugh

aravinda@jhmi.edu (AC); sumeet.chugh@cshs.org (SSC)

Affiliation Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

Competing Interests

Aravinda Chakravarti is a paid member of the Scientific Advisory Board of Affymetrix, a role that is managed by the Committee on Conflict of Interest of the Johns Hopkins University School of Medicine.

Author Contributions

Conceived and designed the experiments: DEA KR AC SSC. Performed the experiments: DEA GH. Analyzed the data: DEA KR WP AAO RJP EB BMP TR NS DSS GLB SSC. Contributed reagents/materials/analysis tools: KR JJ EB BMP GFT EM PMS SSC. Wrote the paper: DEA KR AC SSC.