About the Authors

Guido Krebiehl

Affiliation Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

Sabine Ruckerbauer

Affiliation Autophagy Laboratory, Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, Germany

Lena F. Burbulla

Affiliations Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, Graduate School of Cellular and Molecular Neuroscience, University of Tuebingen, Tübingen, Germany

Nicole Kieper

Affiliation Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

Brigitte Maurer

Affiliation Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

Jens Waak

Current address: Nexigen GmbH, Bonn, Germany

Affiliation Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

Hartwig Wolburg

Affiliation Institute of Pathology, University of Tübingen, Tübingen, Germany

Zemfira Gizatullina

Affiliation Department of Neurology, Otto von Guericke University of Magdeburg, Magdeburg, Germany

Frank N. Gellerich

Affiliation KeyNeurotek Pharmaceuticals AG, ZENIT, Magdeburg, Germany

Dirk Woitalla

Affiliation Department of Neurology, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany

Olaf Riess

Affiliation Department of Medical Genetics, University of Tübingen, Tübingen, Germany

Philipp J. Kahle

Affiliation Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

Tassula Proikas-Cezanne

tassula.proikas-cezanne@uni-tuebingen.de (TP-C); rejko.krueger@uni-tuebingen.de (RK)

Affiliation Autophagy Laboratory, Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, Germany

Rejko Krüger

tassula.proikas-cezanne@uni-tuebingen.de (TP-C); rejko.krueger@uni-tuebingen.de (RK)

Affiliation Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

Competing Interests

One of the authors is employed by a commercial company, (i.e. KeyNeurotek Pharmaceuticals). This company therefore may formally act as a funder due to employment of one authors of this study. However, this funder did not play any role in this study, since only the expertise of FNG in terms of respirometry Figure 1 independently from his affiliation was subject of cooperation. Therefore no financial disclosure or specification of the role of the funder needs to be declared.

Author Contributions

Conceived and designed the experiments: GK TPC RK. Performed the experiments: GK SR NK BM HW ZG. Analyzed the data: GK LFB HW FNG OR TPC RK. Contributed reagents/materials/analysis tools: JW DW PK RK. Wrote the paper: RK.