About the Authors

Johannes Brettschneider

Affiliation Department of Neurology, University of Ulm, Ulm, Germany

Hayrettin Tumani

hayrettin.tumani@uni-ulm.de

Affiliation Department of Neurology, University of Ulm, Ulm, Germany

Ulrike Kiechle

Affiliation Department of Neurology, University of Ulm, Ulm, Germany

Rainer Muche

Affiliation Institute for Biometry, University of Ulm, Ulm, Germany

Gayle Richards

Affiliation Genzyme Virotech, Rüsselsheim, Germany

Vera Lehmensiek

Affiliation Department of Neurology, University of Ulm, Ulm, Germany

Albert C. Ludolph

Affiliation Department of Neurology, University of Ulm, Ulm, Germany

Markus Otto

Affiliation Department of Neurology, University of Ulm, Ulm, Germany

Competing Interests

GR is a paid employee of Genzyme Virotech. She contributed to the manuscript by performing the ELISA assays blinded to all other data. She was not involved in study design, data analysis or the decision to publish this manuscript. All other authors have no competing interests to disclose. The authors hereby declare that this does not alter the adherence of all authors to the PLoS One policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HT AL MO. Performed the experiments: UK GR VL. Analyzed the data: JB HT UK RM VL MO. Contributed reagents/materials/analysis tools: JB HT RM GR. Wrote the paper: JB HT UK RM VL AL MO. Performed the ELISA tests blinded to the clinical data: GR.