HIV-1 Infection of DC: Evidence for the Acquisition of Virus Particles from Infected T Cells by Antigen Uptake Mechanism

Narasimhan J. Venkatachari; Sean Alber; Simon C. Watkins; Velpandi Ayyavoo

doi:10.1371/journal.pone.0007470

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Open Access

Peer-reviewed

Research Article

HIV-1 Infection of DC: Evidence for the Acquisition of Virus Particles from Infected T Cells by Antigen Uptake Mechanism

Narasimhan J. Venkatachari,

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Sean Alber,

Affiliation Department of Cell Biology and Physiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Simon C. Watkins,

Affiliation Department of Cell Biology and Physiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Velpandi Ayyavoo

* E-mail: velpandi@pitt.edu

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯

HIV-1 Infection of DC: Evidence for the Acquisition of Virus Particles from Infected T Cells by Antigen Uptake Mechanism

Narasimhan J. Venkatachari,
Sean Alber,
Simon C. Watkins,
Velpandi Ayyavoo

Published: October 15, 2009
https://doi.org/10.1371/journal.pone.0007470

About the Authors

Narasimhan J. Venkatachari

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Sean Alber

Affiliation Department of Cell Biology and Physiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Simon C. Watkins

Affiliation Department of Cell Biology and Physiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Velpandi Ayyavoo

* E-mail: velpandi@pitt.edu

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NJV VA. Performed the experiments: NJV SA. Analyzed the data: NJV SCW VA. Contributed reagents/materials/analysis tools: SA SCW. Wrote the paper: NJV VA.

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T cells
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HIV-1
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Flow cytometry
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Lymphocytes
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Cell staining
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T cell receptors
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Cell membranes
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Antibodies
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