About the Authors

Hyoung-gon Lee

hyoung-gon.lee@case.edu (HgL); mark.smith@case.edu (MAS)

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Qun Chen

Affiliation Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America

Julie A. Wolfram

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Sandy L. Richardson

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Anna Liner

Affiliations Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America

Sandra L. Siedlak

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Xiongwei Zhu

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Nicholas P. Ziats

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Hisashi Fujioka

Affiliation Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America

Dean W. Felsher

Affiliation Division of Oncology, Department of Medicine and Pathology, Stanford University School of Medicine, Stanford, California, United States of America

Rudy J. Castellani

Affiliation Department of Pathology, University of Maryland, Baltimore, Maryland, United States of America

Maria L. Valencik

Affiliation Department of Biochemistry, University of Nevada Reno, Reno, Nevada, United States of America

John A. McDonald

Affiliation Department of Biochemistry, University of Nevada Reno, Reno, Nevada, United States of America

Brian D. Hoit

Affiliations Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America

Edward J. Lesnefsky

Address Current address: Department of Medicine, Division of Cardiology, Virginia Commonwealth University, and McGuire DVAMC, Richmond, Virginia, United States of America

Affiliations Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, Louis Stokes Cleveland DVAMC, Cleveland, Ohio, United States of America

Mark A. Smith

hyoung-gon.lee@case.edu (HgL); mark.smith@case.edu (MAS)

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MAS. Performed the experiments: HgL QC SLR AL SLS HF BDH EJL. Analyzed the data: HgL JAW AL SLS XZ NPZ HF DWF RJC MLV JAM BDH EJL MAS. Contributed reagents/materials/analysis tools: DWF. Wrote the paper: HgL SLS BDH EJL MAS.