About the Authors

Siim Sõber

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Elin Org

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Katrin Kepp

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Peeter Juhanson

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Susana Eyheramendy

Affiliations Institute of Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany, Department of Statistics, Pontificia Universidad Catolica de Chile, Santiago, Chile

Christian Gieger

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany

Peter Lichtner

Affiliation Institute of Human Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany

Norman Klopp

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany

Gudrun Veldre

Affiliations Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Department of Cardiology, University of Tartu, Tartu, Estonia

Margus Viigimaa

Affiliation Centre of Cardiology, North Estonia Medical Centre, Tallinn, Estonia

Angela Döring

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany

for the Kooperative Gesundheitsforschung in der Region Augsburg study
Margus Putku

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Piret Kelgo

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

for the HYPertension in ESTonia study
Sue Shaw-Hawkins

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Philip Howard

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Abiodun Onipinla

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Richard J. Dobson

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Stephen J. Newhouse

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Morris Brown

Affiliation Clinical Pharmacology Unit, University of Cambridge, Addenbrookes Hospital, Cambridge, United Kingdom

Anna Dominiczak

Affiliation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom

John Connell

Affiliation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom

Nilesh Samani

Affiliation Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom

Martin Farrall

Affiliation Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

for the MRC British Genetics of Hypertension study
Mark J. Caulfield

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Patricia B. Munroe

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Thomas Illig

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany

H.-Erich Wichmann

Affiliations Institute of Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

Thomas Meitinger

Affiliations Institute of Human Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany, Institute of Human Genetics, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Maris Laan

maris.laan@ut.ee

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS EO KK ML. Performed the experiments: SS EO PJ PL NK PK SSH PH AKO RD TI. Analyzed the data: SS EO KK SE CG SJN ML. Contributed reagents/materials/analysis tools: SE MV MJC PM TI HEW TM ML. Wrote the paper: SS ML. HYPEST sample collection: Acquisition of the phenotype data: ML EO PJ GV MV MP PK. KORA cohort: Acquisition of the phenotype data: CG AD TI HEW. BRIGHT sample collection: Acquisition of the phenotype data: MB AD JC NJS MF MJC PM.