About the Authors

Cheryl I. Champion

Affiliation Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Valerie A. Kickhoefer

Affiliation Department of Biological Chemistry, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Guangchao Liu

Affiliation Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Raymond J. Moniz

Affiliation Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Amanda S. Freed

Affiliation Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Liisa L. Bergmann

Affiliation Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Dana Vaccari

Affiliation Department of Biological Chemistry, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Sujna Raval-Fernandes

Affiliation Department of Biological Chemistry, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America

Ann M. Chan

Affiliations Department of Ophthalmology, University of California Los Angeles, Los Angeles, California, United States of America, Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California, United States of America

Leonard H. Rome

Affiliations Department of Biological Chemistry, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America, California NanoSystems Institute, University of California Los Angeles, Los Angeles, California, United States of America

Kathleen A. Kelly

kkelly@mednet.ucla.edu

Affiliations Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America, California NanoSystems Institute, University of California Los Angeles, Los Angeles, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CIC VAK LHR KAK. Performed the experiments: CIC VAK GL RJM ASF LLB DV SRF AMC KAK. Analyzed the data: CIC VAK GL RJM ASF LLB DV SRF AMC LHR KAK. Contributed reagents/materials/analysis tools: LHR. Wrote the paper: CIC VAK LHR KAK. Developed the MOMP-vault using the vault platform: KK CIC VK LHR. Originator of the idea of using vaults as a platform for vaccines: KK LHR. Designed the immunization protocols: KK. Responsible for designing the MOMP fused to the INT domain and producing and evaluating the recombinant vaults: VK LHR.