Cardiac Expression of Microsomal Triglyceride Transfer Protein Is Increased in Obesity and Serves to Attenuate Cardiac Triglyceride Accumulation

Emil D. Bartels; Jan M. Nielsen; Lars I. Hellgren; Thorkil Ploug; Lars B. Nielsen

doi:10.1371/journal.pone.0005300

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Peer-reviewed

Research Article

Cardiac Expression of Microsomal Triglyceride Transfer Protein Is Increased in Obesity and Serves to Attenuate Cardiac Triglyceride Accumulation

Emil D. Bartels,

Affiliation Department of Clinical Biochemistry, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
⨯
Jan M. Nielsen,

Affiliation Department of Cardiology, Aarhus University Hospital, Skejby, Denmark
⨯
Lars I. Hellgren,

Affiliation Department of Systems Biology and Centre for Advanced Food Studies, Technical University of Denmark, Lyngby, Denmark
⨯
Thorkil Ploug,

Affiliation Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Lars B. Nielsen

* E-mail: larsbo@rh.dk

Affiliations Department of Clinical Biochemistry, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
⨯

Cardiac Expression of Microsomal Triglyceride Transfer Protein Is Increased in Obesity and Serves to Attenuate Cardiac Triglyceride Accumulation

Emil D. Bartels,
Jan M. Nielsen,
Lars I. Hellgren,
Thorkil Ploug,
Lars B. Nielsen

Published: April 23, 2009
https://doi.org/10.1371/journal.pone.0005300

About the Authors

Emil D. Bartels

Affiliation Department of Clinical Biochemistry, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

Jan M. Nielsen

Affiliation Department of Cardiology, Aarhus University Hospital, Skejby, Denmark

Lars I. Hellgren

Affiliation Department of Systems Biology and Centre for Advanced Food Studies, Technical University of Denmark, Lyngby, Denmark

Thorkil Ploug

Affiliation Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark

Lars B. Nielsen

* E-mail: larsbo@rh.dk

Affiliations Department of Clinical Biochemistry, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EDB LBN. Performed the experiments: EDB JMN. Analyzed the data: EDB JMN LIH TP. Contributed reagents/materials/analysis tools: EDB JMN LIH TP LBN. Wrote the paper: EDB LBN.

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Heart
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Obesity
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Fatty acids
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Lipid metabolism
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Gene expression
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Lipids
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Glucose metabolism
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