About the Authors

Fumihiko Nakamura

fnakamura@rics.bwh.harvard.edu

Affiliation Translational Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Outi Heikkinen

Affiliation Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, Helsinki, Finland

Olli T. Pentikäinen

Affiliation Department of Biological and Environmental Science, University of Jyväskylä, Jyväskylä, Finland

Teresia M. Osborn

Affiliation Translational Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Karen E. Kasza

Affiliation Department of Physics & SEAS, Harvard University, Cambridge, Massachusetts, United States of America

David A. Weitz

Affiliation Department of Physics & SEAS, Harvard University, Cambridge, Massachusetts, United States of America

Olga Kupiainen

Affiliation Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, Helsinki, Finland

Perttu Permi

Affiliation Program in Structural Biology and Biophysics, Institute of Biotechnology, University of Helsinki, Helsinki, Finland

Ilkka Kilpeläinen

Affiliation Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, Helsinki, Finland

Jari Ylänne

Affiliation Department of Biological and Environmental Science, University of Jyväskylä, Jyväskylä, Finland

John H. Hartwig

Affiliation Translational Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Thomas P. Stossel

Affiliation Translational Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FN OH OTP IK JY JHH TPS. Performed the experiments: FN OH OTP TMO KEK PP. Analyzed the data: FN OH OTP TMO KEK OK PP JY. Contributed reagents/materials/analysis tools: FN OH OTP DW IK JY JHH TPS. Wrote the paper: FN OH OTP TMO KEK PP JY JHH TPS.