RNAi Methodologies for the Functional Study of Signaling Molecules

Gwang Lee; Leah A. Santat; Mi Sook Chang; Sangdun Choi

doi:10.1371/journal.pone.0004559

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Open Access

Peer-reviewed

Research Article

RNAi Methodologies for the Functional Study of Signaling Molecules

Gwang Lee,

Affiliations Department of Molecular Science and Technology, College of Natural Science, Ajou University, Suwon, Korea, Institute for Medical Sciences, College of Natural Science, Ajou University, Suwon, Korea
⨯
Leah A. Santat,

Affiliation Molecular Biology Laboratory, Alliance for Cellular Signaling, Division of Biology, California Institute of Technology, Pasadena, California, United States of America
⨯
Mi Sook Chang,

Affiliation Molecular Biology Laboratory, Alliance for Cellular Signaling, Division of Biology, California Institute of Technology, Pasadena, California, United States of America
⨯
Sangdun Choi

* E-mail: sangdunchoi@ajou.ac.kr

Affiliations Department of Molecular Science and Technology, College of Natural Science, Ajou University, Suwon, Korea, Department of Biological Sciences, College of Natural Science, Ajou University, Suwon, Korea
⨯

RNAi Methodologies for the Functional Study of Signaling Molecules

Gwang Lee,
Leah A. Santat,
Mi Sook Chang,
Sangdun Choi

Published: February 24, 2009
https://doi.org/10.1371/journal.pone.0004559

About the Authors

Gwang Lee

Affiliations Department of Molecular Science and Technology, College of Natural Science, Ajou University, Suwon, Korea, Institute for Medical Sciences, College of Natural Science, Ajou University, Suwon, Korea

Leah A. Santat

Affiliation Molecular Biology Laboratory, Alliance for Cellular Signaling, Division of Biology, California Institute of Technology, Pasadena, California, United States of America

Mi Sook Chang

Affiliation Molecular Biology Laboratory, Alliance for Cellular Signaling, Division of Biology, California Institute of Technology, Pasadena, California, United States of America

Sangdun Choi

* E-mail: sangdunchoi@ajou.ac.kr

Affiliations Department of Molecular Science and Technology, College of Natural Science, Ajou University, Suwon, Korea, Department of Biological Sciences, College of Natural Science, Ajou University, Suwon, Korea

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GL SC. Performed the experiments: LAS MSC. Wrote the paper: GL SC.

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Small interfering RNA
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RNA interference
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Gene expression
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Transfection
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Microarrays
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Reverse transcriptase-polymerase chain reaction
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Gene regulation
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G-protein signaling
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