Monoallelic Expression of Multiple Genes in the CNS

Jinhui Wang; Zuzana Valo; David Smith; Judith Singer-Sam

doi:10.1371/journal.pone.0001293

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Open Access

Peer-reviewed

Research Article

Monoallelic Expression of Multiple Genes in the CNS

Jinhui Wang,

Affiliations Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
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Zuzana Valo,

Affiliations Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
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David Smith,

Affiliation Division of Information Sciences, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
⨯
Judith Singer-Sam

*To whom correspondence should be addressed. E-mail: jsam@coh.org

Affiliations Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
⨯

Monoallelic Expression of Multiple Genes in the CNS

Jinhui Wang,
Zuzana Valo,
David Smith,
Judith Singer-Sam

Published: December 12, 2007
https://doi.org/10.1371/journal.pone.0001293

About the Authors

Jinhui Wang

Affiliations Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

Zuzana Valo

David Smith

Affiliation Division of Information Sciences, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

Judith Singer-Sam

*To whom correspondence should be addressed. E-mail: jsam@coh.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JS JW. Performed the experiments: JW ZV. Analyzed the data: JS JW ZV. Contributed reagents/materials/analysis tools: DS. Wrote the paper: JS JW ZV DS.

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DNA methylation
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Gene expression
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Polymerase chain reaction
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DNA
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Reverse transcriptase-polymerase chain reaction
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Central nervous system
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DNA transcription
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Signal amplification
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