Nullomers: Really a Matter of Natural Selection?

Claudia Acquisti; George Poste; David Curtiss; Sudhir Kumar

doi:10.1371/journal.pone.0001022

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Open Access

Peer-reviewed

Research Article

Nullomers: Really a Matter of Natural Selection?

Claudia Acquisti,

Affiliations Center for Evolutionary Functional Genomics, Arizona State University, Tempe, Arizona, United States of America, The Biodesign Institute and the School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America
⨯
George Poste,

Affiliation The Biodesign Institute and the School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America
⨯
David Curtiss,

Affiliation Center for Evolutionary Functional Genomics, Arizona State University, Tempe, Arizona, United States of America
⨯
Sudhir Kumar

*To whom correspondence should be addressed. E-mail: s.kumar@asu.edu

Affiliations Center for Evolutionary Functional Genomics, Arizona State University, Tempe, Arizona, United States of America, The Biodesign Institute and the School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America
⨯

Nullomers: Really a Matter of Natural Selection?

Claudia Acquisti,
George Poste,
David Curtiss,
Sudhir Kumar

Published: October 10, 2007
https://doi.org/10.1371/journal.pone.0001022

About the Authors

Claudia Acquisti

Affiliations Center for Evolutionary Functional Genomics, Arizona State University, Tempe, Arizona, United States of America, The Biodesign Institute and the School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America

George Poste

Affiliation The Biodesign Institute and the School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America

David Curtiss

Affiliation Center for Evolutionary Functional Genomics, Arizona State University, Tempe, Arizona, United States of America

Sudhir Kumar

*To whom correspondence should be addressed. E-mail: s.kumar@asu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SK GP. Performed the experiments: CA. Analyzed the data: CA. Contributed reagents/materials/analysis tools: CA DC. Wrote the paper: SK CA.

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Human genomics
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Mammalian genomics
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Point mutation
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DNA methylation
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Chimpanzees
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Sequence motif analysis
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Natural selection
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Nucleotides
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