Biphasic Hoxd Gene Expression in Shark Paired Fins Reveals an Ancient Origin of the Distal Limb Domain

Renata Freitas; GuangJun Zhang; Martin J. Cohn

doi:10.1371/journal.pone.0000754

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Open Access

Peer-reviewed

Research Article

Biphasic Hoxd Gene Expression in Shark Paired Fins Reveals an Ancient Origin of the Distal Limb Domain

Renata Freitas,

Current address: Institute for Molecular and Cell Biology, Porto, Portugal

Affiliation Department of Zoology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United Sates of America
⨯
GuangJun Zhang,

Affiliation Department of Zoology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United Sates of America
⨯
Martin J. Cohn

*To whom correspondence should be addressed. E-mail: cohn@zoo.ufl.edu

Affiliations Department of Zoology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United Sates of America, Department of Anatomy and Cell Biology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United States of America
⨯

Biphasic Hoxd Gene Expression in Shark Paired Fins Reveals an Ancient Origin of the Distal Limb Domain

Renata Freitas,
GuangJun Zhang,
Martin J. Cohn

Published: August 15, 2007
https://doi.org/10.1371/journal.pone.0000754

About the Authors

Renata Freitas

Current address: Institute for Molecular and Cell Biology, Porto, Portugal

Affiliation Department of Zoology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United Sates of America

GuangJun Zhang

Affiliation Department of Zoology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United Sates of America

Martin J. Cohn

*To whom correspondence should be addressed. E-mail: cohn@zoo.ufl.edu

Affiliations Department of Zoology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United Sates of America, Department of Anatomy and Cell Biology, Cancer/Genetics Research Complex, University of Florida, Gainesville, Florida, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MC RF. Performed the experiments: RF GZ. Analyzed the data: MC RF. Wrote the paper: MC RF.

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Gene expression
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Sharks
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Body limbs
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Zebrafish
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Evolutionary genetics
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Cartilage
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Limb buds
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Chondrichthyes
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