About the Authors

Oscar Holmström

Affiliations Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland, Helsinki University Hospital and University of Helsinki, Helsinki, Finland

Nina Linder

Affiliations Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland, Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden

Mikael Lundin

Affiliation Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland

Hannu Moilanen

Affiliation Center of Microscopy and Nanotechnology, University of Oulu, Oulu, Finland

Antti Suutala

Affiliation Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland

Riku Turkki

Affiliation Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland

Heikki Joensuu

Affiliations Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland, Helsinki University Hospital and University of Helsinki, Helsinki, Finland

Jorma Isola

Affiliation BioMediTech, University of Tampere, Tampere, Finland

Vinod Diwan

Affiliation Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden

Johan Lundin

johan.lundin@helsinki.fi

Affiliations Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland, Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden

Competing Interests

Johan Lundin is the founder and co-owner of Fimmic Oy, Helsinki, Finland. Jorma Isola is the founder and owner of Jilab Inc, Tampere, Finland. The authors confirm that these interests do not alter their adherence to the data and material sharing policies of PLOS ONE.

Author Contributions

Conceived and designed the experiments: JL OH VD. Performed the experiments: OH RT. Analyzed the data: OH JL. Contributed reagents/materials/analysis tools: HM AS ML JL VD JI. Wrote the paper: OH JL NL HJ. Commented the manuscript: OH NL ML HM AS RT HJ JI VD JL. Supervised the project: JL.