About the Authors

David A. Johnson

dajevms@aol.com

Affiliation Gastroenterology Division, Eastern VA Medical School, Norfolk, Virginia, United States of America

Robert L. Barclay

Affiliation Rockford Gastroenterology Associates, Ltd., Rockford, Illinois, United States of America

Klaus Mergener

Affiliation Digestive Health Specialists, Tacoma, Washington, United States of America

Gunter Weiss

Affiliation Epigenomics AG, Berlin Germany

Thomas König

Affiliation Epigenomics AG, Berlin Germany

Jürgen Beck

Affiliation Epigenomics AG, Berlin Germany

Nicholas T. Potter

Affiliation Molecular Pathology Laboratory Network, Inc., Maryville, Tennessee, United States of America

Competing Interests

The authors have read the journal’s policy and have the following conflicts: David A. Johnson MD: •Consultant/clinical investigator- Epigenomics. •Advisory Board Given Imaging, CRH Medical, Abbivie, Jansen/Centacor, Takeda, AstraZeneca, Phizer, Medivo •Clinical investigator – EXACT Sciences. Klaus Mergener, MD, PhD, MBA: •Clinical investigator - Epigenomics •Clinical investigator - GI View Ltd •Clinical investigator - CapsoVision •Consultant/clinical investigator - Intromedic •Consultant, Olympus America •Advisory Board - Colon Prep Center •Advisory Board – angelMD. Robert Barclay, MD: •Clinical investigator - Epigenomics. Gunter Weiss: •Epigenomics employee. Thomas König: •Epigenomics employee. Jürgen Beck: •Epigenomics employee at the time of the study. Nicholas Potter, PhD: •Medical Advisory Board – Epigenomics •Clinical investigator- Epigenomics. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GW TK JB. Performed the experiments: DAJ RLB KM NTP. Analyzed the data: GW TK. Contributed reagents/materials/analysis tools: DAJ RLB KM GW TK JB NTP. Wrote the paper: DAJ RLB KM GW TK JB NTP.