About the Authors

Li Zhou

Contributed equally to this work with: Li Zhou, Meian He, Zengnan Mo

Affiliations MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China, Department of Epidemiology, School of Public Health and Management, Chongqing Medical University, Chongqing, China

Meian He

Contributed equally to this work with: Li Zhou, Meian He, Zengnan Mo

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Zengnan Mo

Contributed equally to this work with: Li Zhou, Meian He, Zengnan Mo

wut@mails.tjmu.edu.cn (TW); zengnanmo@hotmail.com (ZM)

Affiliation Institute of Urology and Nephrology, First Affiliated Hospital & Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China

Chen Wu

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Handong Yang

Affiliation Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, China

Dianke Yu

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Xiaobo Yang

Affiliation Institute of Urology and Nephrology, First Affiliated Hospital & Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China

Xiaomin Zhang

Affiliations MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China, Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

Yiqin Wang

Affiliation Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China

Jielin Sun

Affiliation Fudan University Institute of Urology, Huashan Hospital, & Fudan-VARI Center for Genetic Epidemiology, School of Life Sciences, Fudan University, Shanghai, China

Yong Gao

Affiliation Institute of Urology and Nephrology, First Affiliated Hospital & Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China

Aihua Tan

Affiliation Institute of Urology and Nephrology, First Affiliated Hospital & Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China

Yunfeng He

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Haiying Zhang

Affiliation Institute of Urology and Nephrology, First Affiliated Hospital & Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China

Xue Qin

Affiliation Institute of Urology and Nephrology, First Affiliated Hospital & Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China

Jingwen Zhu

Affiliation Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China

Huaixing Li

Affiliation Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China

Xu Lin

Affiliation Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China

Jiang Zhu

Affiliation Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, China

Xinwen Min

Affiliation Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, China

Mingjian Lang

Affiliation Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, China

Dongfeng Li

Affiliation Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, Hubei, China

Kan Zhai

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Jiang Chang

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Wen Tan

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Jing Yuan

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Weihong Chen

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Youjie Wang

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Sheng Wei

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Xiaoping Miao

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Feng Wang

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Weimin Fang

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Yuan Liang

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Qifei Deng

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Xiayun Dai

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Dafeng Lin

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Suli Huang

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Huan Guo

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

S. Lilly Zheng

Affiliation Fudan University Institute of Urology, Huashan Hospital, & Fudan-VARI Center for Genetic Epidemiology, School of Life Sciences, Fudan University, Shanghai, China

Jianfeng Xu

Affiliation Fudan University Institute of Urology, Huashan Hospital, & Fudan-VARI Center for Genetic Epidemiology, School of Life Sciences, Fudan University, Shanghai, China

Dongxin Lin

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Frank B. Hu

Affiliation Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

Tangchun Wu

wut@mails.tjmu.edu.cn (TW); zengnanmo@hotmail.com (ZM)

Affiliation MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LZ ZM XZ XL JX Dongxin Lin FBH TW. Performed the experiments: ZM CW HY Youjie Wang AT Jiang Zhu HL ML Dafeng Lin KZ JY WC WF YL QD SH SLZ. Analyzed the data: LZ MH YH SW X. Miao FW HG TW. Contributed reagents/materials/analysis tools: ZM CW HY DY XY JS YG HZ XQ Jingwen Zhu X. Min JC WT Yiqin Wang SW XD Dongfeng Lin. Wrote the manuscript: LZ MH FBH TW. Conceived and designed the experiments: LZ(Li Zhou) ZM(Zengnan Mo) XZ(Xiaomin Zhang) XL(Xu Lin) JX(Jianfeng Xu)) DL(Dongxin Lin) FBH( Frank B.Hu) TW(Tangchun Wu) Performed the experiments: ZM(Zengnan Mo) CW(Chen Wu) HY(Handong Yang) YW(Youjie Wang) AT(Aihua Tan) JZ(Jiang Zhu) HL(Huaxing Li) ML(Mingjian Lang) DL(Dafeng Lin) KZ(Kan Zhai) JY(Jing Yuan) WC((Weihong Chen)) WF(Weimin Fang) YL(Yuan Liang)) QD(Qifei Deng) SH(Suli Huang)) SLZ(S.Lilly Zheng)) Analyzed the Data: LZ(Li Zhou) MH(Meian He) YH(Yunfeng He) SW(Sheng Wei)) XM(Xiaoping Miao) FW( Feng Wang) HG(Huan Guo) TW(Tangchun Wu) Contributed reagents/materials/analysis tools: ZM(Zengnan Mo) CW(Chen Wu) HY(Handong Yang) DY(Dianke Yu) XY(Xiaobo Yang) JS(Jielin Sun) YG(Yong Gao) HZ(Haiying Zhang)) XQ(Xue Qin) JZ(Jingwen Zhu) XM(Xinwen Min) JC(Jiang Chang) WT(Wen Tan) YW(Yiqin Wang) SW(Sheng Wei) XD(Xiayun Dai) DL(Dongfeng Li).