About the Authors

Aae Suzuki

Affiliation Department of Hematology/Oncology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Jae-Won Shin

Affiliation Pharmacology Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Yuhuan Wang

Affiliation Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Sang H. Min

Affiliation Department of Hematology/Oncology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Morty Poncz

Affiliation Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

John K. Choi

Affiliation Hematopathology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Dennis E. Discher

Affiliation Pharmacology Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Chris L. Carpenter

Affiliation Clinical Oncology, GlaxoSmithKline, Philadelphia, Pennsylvania, United States of America

Lurong Lian

Affiliation Department of Hematology/Oncology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Liang Zhao

Affiliation Department of Hematology/Oncology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Yangfeng Wang

Affiliation Department of Hematology/Oncology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Charles S. Abrams

abrams@mail.med.upenn.edu

Affiliation Department of Hematology/Oncology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

Co-author CL Carpenter is employed by GlaxoSmithKline. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CSA MP JWS DED CLC. Performed the experiments: AS YW JWS SHM JKC LL LZ YW. Analyzed the data: AS YW JWS JKC CSA MP YW. Contributed reagents/materials/analysis tools: CSA DED CLC MP JKC. Wrote the paper: AS JWS YW SHM MP JKC DED CLC LL LZ YW CSA.