About the Authors

Gang Chen

Contributed equally to this work with: Gang Chen, Ijeoma Adaku Umelo

Affiliations Department of Pathology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, People's Republic of China, Laboratory of Medical and Molecular Oncology, Department of Medical Oncology, Oncology Center, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Ijeoma Adaku Umelo

Contributed equally to this work with: Gang Chen, Ijeoma Adaku Umelo

Affiliation Laboratory of Medical and Molecular Oncology, Department of Medical Oncology, Oncology Center, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Shasha Lv

Affiliation Laboratory of Medical and Molecular Oncology, Department of Medical Oncology, Oncology Center, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Erik Teugels

Affiliation Laboratory of Medical and Molecular Oncology, Department of Medical Oncology, Oncology Center, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Karel Fostier

Affiliation Laboratory of Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium

Peter Kronenberger

Affiliations Laboratory of Medical and Molecular Oncology, Department of Medical Oncology, Oncology Center, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium, Laboratory for Biotechnology, Department of Gezondheidszorg, Erasmushogeschool Brussel, Brussels, Belgium

Alex Dewaele

Affiliation Laboratory of Medical and Molecular Oncology, Department of Medical Oncology, Oncology Center, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Jan Sadones

Affiliation Department of Pathology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Caroline Geers

Affiliation Department of Pathology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Jacques De Grève

Jacques.Degreve@uzbrussel.be

Affiliation Laboratory of Medical and Molecular Oncology, Department of Medical Oncology, Oncology Center, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

Competing Interests

The authors received funding from a commercial source: Boehringer Ingelheim GmbH. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GC ET KF PK JDG. Performed the experiments: GC IAU SL KF JS. Analyzed the data: GC SL AD JS CG. Contributed reagents/materials/analysis tools: KF AD JS CG. Wrote the paper: GC IAU SL ET KF PK JDG.