About the Authors

Brian T. Kalish

Affiliation Department of Surgery and The Vascular Biology Program, Boston Children’s Hospital, Boston, Massachusetts, United States of America

Hau D. Le

Affiliations Department of Surgery and The Vascular Biology Program, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

Kathleen M. Gura

Affiliation Department of Pharmacy, Boston Children’s Hospital, Boston, Massachusetts, United States of America

Bruce R. Bistrian

Affiliation Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

Mark Puder

mark.puder@childrens.harvard.edu

Affiliation Department of Surgery and The Vascular Biology Program, Boston Children’s Hospital, Boston, Massachusetts, United States of America

Competing Interests

A license agreement for the use of Omegaven® has been signed by Boston Children’s Hospital and Fresenius Kabi and a patent has been submitted by Boston Children’s Hospital on behalf of MP and KMG. Metabolon performed the metabolomic profiling and provided technical advice and analysis for this study. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors. The patent application number is 20080275119 and the title of the patent application is “Treatment and Prevention of Liver Disease Associated with Parenteral Nutrition.

Author Contributions

Conceived and designed the experiments: BTK HDL MP. Performed the experiments: BTK HDL. Analyzed the data: BTK HDL BRB MP. Contributed reagents/materials/analysis tools: KMG. Wrote the paper: BTK HDL BRB MP.