Comparative Analysis of DNA Word Abundances in Four Yeast Genomes Using a Novel Statistical Background Model

Ramkumar Hariharan; Reji Simon; M. Radhakrishna Pillai; Todd D. Taylor

doi:10.1371/journal.pone.0058038

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Open Access

Peer-reviewed

Research Article

Comparative Analysis of DNA Word Abundances in Four Yeast Genomes Using a Novel Statistical Background Model

Ramkumar Hariharan,

Current address: Institute for Systems Biology, Seattle, Washington, United States of America

Affiliations Cancer Research Program, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, Kerala, India, Laboratory for MetaSystems Research, RIKEN Quantitative Biology Center, Tsurumi-ku, Yokohama, Kanagawa, Japan
⨯
Reji Simon,

Affiliation Cancer Research Program, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, Kerala, India
⨯
M. Radhakrishna Pillai,

Affiliation Cancer Research Program, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, Kerala, India
⨯
Todd D. Taylor

* E-mail: taylor@riken.jp

Affiliation Laboratory for MetaSystems Research, RIKEN Quantitative Biology Center, Tsurumi-ku, Yokohama, Kanagawa, Japan
⨯

Comparative Analysis of DNA Word Abundances in Four Yeast Genomes Using a Novel Statistical Background Model

Ramkumar Hariharan,
Reji Simon,
M. Radhakrishna Pillai,
Todd D. Taylor

Published: March 5, 2013
https://doi.org/10.1371/journal.pone.0058038

About the Authors

Ramkumar Hariharan

Current address: Institute for Systems Biology, Seattle, Washington, United States of America

Affiliations Cancer Research Program, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, Kerala, India, Laboratory for MetaSystems Research, RIKEN Quantitative Biology Center, Tsurumi-ku, Yokohama, Kanagawa, Japan

Reji Simon

Affiliation Cancer Research Program, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, Kerala, India

M. Radhakrishna Pillai

Affiliation Cancer Research Program, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, Kerala, India

Todd D. Taylor

* E-mail: taylor@riken.jp

Affiliation Laboratory for MetaSystems Research, RIKEN Quantitative Biology Center, Tsurumi-ku, Yokohama, Kanagawa, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RH TDT. Performed the experiments: RH RS. Analyzed the data: RH TDT. Contributed reagents/materials/analysis tools: RS MRP. Wrote the paper: RH MRP TDT.

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Yeast
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Genomics
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Markov models
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Saccharomyces cerevisiae
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Binomials
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