About the Authors
- Yan Lu
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* E-mail: luy@svm.vetmed.wisc.edu (YL); wlmurphy@wisc.edu (WLM)
Affiliations Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconson, United States of America, Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconson, United States of America
- Jae Sung Lee
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Affiliation Departments of Biomedical Engineering, University of Wisconsin, Madison, Wisconson, United States of America
- Brett Nemke
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Affiliation Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconson, United States of America
- Ben K. Graf
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Affiliation Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconson, United States of America
- Kevin Royalty
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Affiliation Departments of Biomedical Engineering, University of Wisconsin, Madison, Wisconson, United States of America
- Richard Illgen III
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Affiliation Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconson, United States of America
- Ray Vanderby Jr
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Affiliation Departments of Biomedical Engineering, University of Wisconsin, Madison, Wisconson, United States of America
- Mark D. Markel
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Affiliations Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconson, United States of America, Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconson, United States of America
- William L. Murphy
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* E-mail: luy@svm.vetmed.wisc.edu (YL); wlmurphy@wisc.edu (WLM)
Affiliations Departments of Biomedical Engineering, University of Wisconsin, Madison, Wisconson, United States of America, Pharmacology, University of Wisconsin, Madison, Wisconson, United States of America, Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconson, United States of America
Competing Interests
Smith&Nephew, Inc., provided titanium implants for this study. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: YL JSL BKG RI RV MDM WLM. Performed the experiments: YL JSL BN. Analyzed the data: YL JSL KR RV MDM WLM. Contributed reagents/materials/analysis tools: JSL KR MDM WLM. Wrote the paper: YL. Proofread the manuscript: MDM, WLM.