About the Authors

Xiao-Xin Yan

yanxiaoxin@csu.edu.cn (XXY); grose@siumed.edu (GMR); ppatrylo@siu.edu (PRP)

Affiliation Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China

Yan Cai

Affiliations Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China, Center for Integrated Research in Cognitive and Neural Sciences, Southern Illinois University Carbondale, Illinois, United States of America, Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

Jarod Shelton

Affiliation Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

Si-Hao Deng

Affiliation Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China

Xue-Gang Luo

Affiliation Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China

Salvatore Oddo

Affiliation Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

Frank M. LaFerla

Affiliation Department of Neurobiology and Behavior, University of California Irvine, Irvine, California, United States of America

Huaibin Cai

Affiliation Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America

Gregory M. Rose

yanxiaoxin@csu.edu.cn (XXY); grose@siumed.edu (GMR); ppatrylo@siu.edu (PRP)

Affiliations Center for Integrated Research in Cognitive and Neural Sciences, Southern Illinois University Carbondale, Illinois, United States of America, Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

Peter R. Patrylo

yanxiaoxin@csu.edu.cn (XXY); grose@siumed.edu (GMR); ppatrylo@siu.edu (PRP)

Affiliations Center for Integrated Research in Cognitive and Neural Sciences, Southern Illinois University Carbondale, Illinois, United States of America, Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XXY PRP. Performed the experiments: XXY YC JS PRP. Analyzed the data: XXY YC SHD PRP GMR. Contributed reagents/materials/analysis tools: XGL SO FML HC. Wrote the paper: XXY GMR PRP.