About the Authors

Ming-Fei Lang

Affiliation Department of Neurosciences, Center for Gene Expression and Drug Discovery, Cancer Center, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Su Yang

Contributed equally to this work with: Su Yang, Chunnian Zhao, Guoqiang Sun

Affiliations Department of Neurosciences, Center for Gene Expression and Drug Discovery, Cancer Center, Beckman Research Institute of City of Hope, Duarte, California, United States of America, Irell & Manella Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Chunnian Zhao

Contributed equally to this work with: Su Yang, Chunnian Zhao, Guoqiang Sun

Affiliation Department of Neurosciences, Center for Gene Expression and Drug Discovery, Cancer Center, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Guoqiang Sun

Contributed equally to this work with: Su Yang, Chunnian Zhao, Guoqiang Sun

Affiliation Department of Neurosciences, Center for Gene Expression and Drug Discovery, Cancer Center, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Kiyohito Murai

Affiliation Department of Neurosciences, Center for Gene Expression and Drug Discovery, Cancer Center, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Xiwei Wu

Affiliation Department of Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Jinhui Wang

Affiliation DNA sequencing/Solexa Core, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Hanlin Gao

Affiliation DNA sequencing/Solexa Core, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Christine E. Brown

Affiliation Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Xiaoxuan Liu

Affiliation Centre Interdisciplinaire de Nanoscience de Marseille, CNRS UMR 7325, Aix-Marseille University, Marseille, France

Jiehua Zhou

Affiliation Department of Molecular and Cellular Biology, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Ling Peng

Affiliation Centre Interdisciplinaire de Nanoscience de Marseille, CNRS UMR 7325, Aix-Marseille University, Marseille, France

John J. Rossi

Affiliations Irell & Manella Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America, Department of Molecular and Cellular Biology, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Yanhong Shi

yshi@coh.org

Affiliations Department of Neurosciences, Center for Gene Expression and Drug Discovery, Cancer Center, Beckman Research Institute of City of Hope, Duarte, California, United States of America, Irell & Manella Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YS. Performed the experiments: ML SY CZ GS KM JW HG. Analyzed the data: ML SY CZ GS KM XW. Contributed reagents/materials/analysis tools: CB XL JZ LP JJR. Wrote the paper: YS ML.