About the Authors

Yan Y. Lam

yan.lam@sydney.edu.au

Affiliation Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, Australia

Connie W. Y. Ha

Affiliation School of Molecular Bioscience, University of Sydney, Sydney, Australia

Craig R. Campbell

Affiliation Discipline of Physiology, Bosch Institute, University of Sydney, Sydney, Australia

Andrew J. Mitchell

Affiliation Molecular Immunopathology Unit, Bosch Institute and Sydney Medical School, University of Sydney, Sydney, Australia

Anuwat Dinudom

Affiliation Discipline of Physiology, Bosch Institute, University of Sydney, Sydney, Australia

Jan Oscarsson

Affiliation AstraZeneca R&D, Mölndal, Sweden

David I. Cook

Affiliation Discipline of Physiology, Bosch Institute, University of Sydney, Sydney, Australia

Nicholas H. Hunt

Affiliation Molecular Immunopathology Unit, Bosch Institute and Sydney Medical School, University of Sydney, Sydney, Australia

Ian D. Caterson

Affiliation Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, Australia

Andrew J. Holmes

Affiliation School of Molecular Bioscience, University of Sydney, Sydney, Australia

Len H. Storlien

Affiliation Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, Australia

Competing Interests

I have read the journal's policy and have the following conflicts: JO and LHS are or have been employed by AstraZeneca. This does not alter our adherence to all the PLoS ONE policies on sharing data and materials. The other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YYL CRC AJM AD DIC NHH IDC AJH LHS JO. Performed the experiments: YYL CWYH JO LHS. Analyzed the data: YYL CWYH AJH. Contributed reagents/materials/analysis tools: YYL CRC AD JO DIC NHH AJH LHS. Wrote the paper: YYL CWYH CRC AJM AD JO DIC NHH IDC LHS.