SWI/SNF and Asf1 Independently Promote Derepression of the DNA Damage Response Genes under Conditions of Replication Stress

Laura V. Minard; Ling-ju Lin; Michael C. Schultz

doi:10.1371/journal.pone.0021633

Loading metrics

Open Access

Peer-reviewed

Research Article

SWI/SNF and Asf1 Independently Promote Derepression of the DNA Damage Response Genes under Conditions of Replication Stress

Laura V. Minard,

Affiliation Department of Biochemistry, School of Molecular and Systems Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
⨯
Ling-ju Lin,

Affiliation Department of Biochemistry, School of Molecular and Systems Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
⨯
Michael C. Schultz

* E-mail: michael.schultz@ualberta.ca

Affiliation Department of Biochemistry, School of Molecular and Systems Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
⨯

SWI/SNF and Asf1 Independently Promote Derepression of the DNA Damage Response Genes under Conditions of Replication Stress

Laura V. Minard,
Ling-ju Lin,
Michael C. Schultz

Published: June 27, 2011
https://doi.org/10.1371/journal.pone.0021633

About the Authors

Laura V. Minard

Affiliation Department of Biochemistry, School of Molecular and Systems Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

Ling-ju Lin

Affiliation Department of Biochemistry, School of Molecular and Systems Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

Michael C. Schultz

* E-mail: michael.schultz@ualberta.ca

Affiliation Department of Biochemistry, School of Molecular and Systems Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MCS. Performed the experiments: LVM LL. Analyzed the data: LVM LL MCS. Contributed reagents/materials/analysis tools: LVM LL. Wrote the paper: LVM MCS.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Acetylation
Is the Subject Area "Acetylation" applicable to this article?

Thanks for your feedback.
DNA replication
Is the Subject Area "DNA replication" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Chromatin
Is the Subject Area "Chromatin" applicable to this article?

Thanks for your feedback.
DNA transcription
Is the Subject Area "DNA transcription" applicable to this article?

Thanks for your feedback.
Synthesis phase
Is the Subject Area "Synthesis phase" applicable to this article?

Thanks for your feedback.
Yeast
Is the Subject Area "Yeast" applicable to this article?

Thanks for your feedback.
Histones
Is the Subject Area "Histones" applicable to this article?

Thanks for your feedback.