About the Authors

Lorenza Mittempergher

Contributed equally to this work with: Lorenza Mittempergher, Jorma J. de Ronde

Affiliation Divisions of Experimental Therapy, Molecular Biology, Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Jorma J. de Ronde

Contributed equally to this work with: Lorenza Mittempergher, Jorma J. de Ronde

Affiliation Divisions of Experimental Therapy, Molecular Biology, Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Marja Nieuwland

Affiliation Central Microarray Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Ron M. Kerkhoven

Affiliation Central Microarray Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Iris Simon

Affiliation Agendia BV, Amsterdam, The Netherlands

Emiel J. Th. Rutgers

Affiliation Divisions of Experimental Therapy, Molecular Biology, Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Lodewyk F. A. Wessels

Affiliation Divisions of Experimental Therapy, Molecular Biology, Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Laura J. Van't Veer

l.vt.veer@nki.nl

Affiliations Divisions of Experimental Therapy, Molecular Biology, Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands, Agendia BV, Amsterdam, The Netherlands

Competing Interests

LJVV is a named inventor on a patent for the 70-gene signature used in this study and is a shareholder in Agendia BV, the commercial entity that markets the 70-gene signature as MammaPrint®. IS is employed by Agendia BV. However, what is stated above does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LM LJVV EJTR. Performed the experiments: LM MN RMK. Analyzed the data: LM JJR LJVV LFAW. Contributed reagents/materials/analysis tools: IS RMK. Wrote the paper: LM JJR LJVV LFAW.