About the Authors

Arno W. R. van Kuijk

Affiliation Division of Clinical Immunology and Rheumatology, F4-218, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

Jeroen DeGroot

Affiliation Business Unit Biosciences, The Netherlands Organization for Applied Scientific Research (TNO) Quality of Life, Leiden, The Netherlands

Rishma C. Koeman

Affiliation Division of Clinical Immunology and Rheumatology, F4-218, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

Nico Sakkee

Affiliation Business Unit Biosciences, The Netherlands Organization for Applied Scientific Research (TNO) Quality of Life, Leiden, The Netherlands

Dominique L. Baeten

Affiliation Division of Clinical Immunology and Rheumatology, F4-218, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

Danielle M. Gerlag

Affiliation Division of Clinical Immunology and Rheumatology, F4-218, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

Paul P. Tak

P.P.Tak@amc.uva.nl

Affiliation Division of Clinical Immunology and Rheumatology, F4-218, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

Competing Interests

PPT served as a consultant to Abbott. JD and NS are employees of the Netherlands Organization for Applied Scientific Research (TNO), which is active in 5 core areas of Quality of Life that deal with health-related research. TNO was founded by law in 1932 to enable business and government to apply knowledge. As a not-for-profit organization regulated by public law, it is an independent research organisation, not part of any government, university or company. The authors confirm their adherence to all the PLoS ONE policies on sharing data and materials, as outlined in detail in the guide for authors http://www.plosone.org/static/policies.action#sharing.

Author Contributions

Conceived and designed the experiments: PPT AWRvK JDG DB DMG. Performed the experiments: JDG RCK NS. Analyzed the data: AWRvK. Contributed reagents/materials/analysis tools: JDG RCK NS DB. Wrote the paper: PPT AWRvK. Performed study visits: AWRvK. Collected serum samples: AWRvK.